4D Molecular Therapeutics Announces Pricing of $300M Public Offering

4D Molecular Therapeutics Announces Pricing of $300M Public Offering

4DMT is a leading clinical-stage genetic medicines company focused on unlocking the full potential of genetic medicines to treat large market diseases in ophthalmology and pulmonology.

Pivot Bio, Iowa State Collaborate for New, $14 Million Ag Research and Education Facility

Pivot Bio, Iowa State Collaborate for New, $14 Million Ag Research and Education Facility

Pivot Bio, a sustainable agriculture company focused on microbial nitrogen, opened its Customer Success Center last week in the Iowa State University Research Park.

Gene Editing Delivery Biotech GenEdit Partners With Genentech, Raises Another $24M

Gene Editing Delivery Biotech GenEdit Partners With Genentech, Raises Another $24M

The multiyear collaboration and licensing pact, disclosed Tuesday morning, comes with $15 million upfront and up to $629 million in biobucks.

FDA Clears AI That Predicts Alzheimer’s Progression From an MRI Scan

FDA Clears AI That Predicts Alzheimer’s Progression From an MRI Scan

The program only requires a common 3D MRI scan, with no contrast injections, as well as cognitive test scores that are typically collected during a diagnostic workup.

ZymoChem Secures $21M Series A Funding Round Led by Breakout Ventures with New Investments from lululemon and Toyota Ventures

ZymoChem Secures $21M Series A Funding Round Led by Breakout Ventures with New Investments from lululemon and Toyota Ventures

ZymoChem will launch its first high-performance material and advance its first partnered product to commercial scale.

Shiseido Long Term Investments for the Future (LIFT) Ventures Invests in Phi Therapeutics

Shiseido Long Term Investments for the Future (LIFT) Ventures Invests in Phi Therapeutics

LIFT Ventures will be a vehicle for investing in innovative early-stage companies within the beauty wellness space.

GigaGen Receives FDA Clearance of IND to Begin Phase 1 Trial of Oncology Drug Candidate, GIGA-564, in Solid Tumors

GigaGen Receives FDA Clearance of IND to Begin Phase 1 Trial of Oncology Drug Candidate, GIGA-564, in Solid Tumors

The Phase 1 trial will be conducted by researchers from the National Cancer Institute as part of a Cooperative Research and Development Agreement. GigaGen anticipates trial initiation in 2024.

Olfa Thera and Opus Bio Win $100K Awards in QB3 Mentoring Program

Olfa Thera and Opus Bio Win $100K Awards in QB3 Mentoring Program

The awards will enable both companies to generate important proof-of-concept data that will help them attract seed investment to grow and develop their technologies and teams.

Glycomine Announces First Pediatric Patient Dosed in Phase 2 Clinical Study of GLM101, a Potential Treatment for PMM2-CDG

Glycomine Announces First Pediatric Patient Dosed in Phase 2 Clinical Study of GLM101, a Potential Treatment for PMM2-CDG

Promising data in adult patients supports advancement into pediatric patients. Data from this portion of the clinical program will inform a pivotal study.

Roche Pushes To Catch Up to Novo Nordisk’s Wegovy With $3.1Bn Deal for Obesity Drugmaker Carmot

Roche Pushes To Catch Up to Novo Nordisk’s Wegovy With $3.1Bn Deal for Obesity Drugmaker Carmot

Existing data on Carmot’s lead medicine “suggests a best-in-class potential to achieve and maintain weight loss with differentiated efficacy.”

FDA Fast Tracks eFFECTOR Therapeutics' Zotatifin Combo for ER+/HER2– Breast Cancer

FDA Fast Tracks eFFECTOR Therapeutics' Zotatifin Combo for ER+/HER2– Breast Cancer

Zotatifin is a sequence-selective small molecule inhibitor of the RNA helicase eIF4A. The drug is designed to inhibit the expression of a cancer-driving protein network.

QBI's Nevan Krogan Leads "Atlas of Autism Protein Interactions" Study

QBI's Nevan Krogan Leads "Atlas of Autism Protein Interactions" Study

Researchers at UCSF have mapped the microscopic world of autism spectrum disorder in unprecedented detail, pointing toward possible therapies for a subset of patients.

Carmot Therapeutics Commenced Phase 2 Clinical Trial of Novel Dual GLP-1/GIP Receptor Agonist CT-868 for the Treatment of Type 1 Diabetes

Carmot Therapeutics Commenced Phase 2 Clinical Trial of Novel Dual GLP-1/GIP Receptor Agonist CT-868 for the Treatment of Type 1 Diabetes

Randomized, placebo-controlled trial to assess 16-week treatment with CT-868 in participants with overweight or obesity with type 1 diabetes.

Delpor's Investigational Risperidone Implant Product Provides Schizophrenia Therapy for up to One Year after a Single Administration in Phase 1b/2a Patient Study

Delpor's Investigational Risperidone Implant Product Provides Schizophrenia Therapy for up to One Year after a Single Administration in Phase 1b/2a Patient Study

Delpor's drug/device combination risperidone implant (DLP-114) was well tolerated for up to 12 months.

GigaGen Presents IND-Enabling Data and Phase 1 Trial Strategy for its Novel Anti-CTLA-4 Oncology Drug Candidate

GigaGen Presents IND-Enabling Data and Phase 1 Trial Strategy for its Novel Anti-CTLA-4 Oncology Drug Candidate

GIGA-564 is a differentiated anti-CTLA-4 antibody with potential to enhance anti-tumor activity and mitigate immune-related toxicities associated with traditional CTLA-4 blockade.

Two Peninsula Drugmakers (Gilead & Assembly Bio) Cut R&D Deal Worth at Least $100M

Two Peninsula Drugmakers (Gilead & Assembly Bio) Cut R&D Deal Worth at Least $100M

Assembly Biosciences will get $100 million upfront in cash and stock in a 12-year research and development pact with Gilead Sciences.

Carmot Therapeutics Highlights Clinical Data from its Pipeline of Treatments for Obesity and Diabetes at ObesityWeek®

Carmot Therapeutics Highlights Clinical Data from its Pipeline of Treatments for Obesity and Diabetes at ObesityWeek®

The results are summarized in three poster presentations taking place at ObesityWeek® in Dallas, October 14-17, 2023.

Bolt Threads, Formerly A Unicorn, Plans SPAC Deal At A $250 Million Valuation

Bolt Threads, Formerly A Unicorn, Plans SPAC Deal At A $250 Million Valuation

Bolt was founded in 2009 to crack the code on growing artificial spider silk.

AbbVie Buys Mitokinin for $110 Million

AbbVie Buys Mitokinin for $110 Million

Mitokinin is developing the “PINK1” activator to correct mitochondrial dysfunction.